Intranasal Midazolam in Children as a Pre-Operative Sedative - Part 2
Status:
Completed
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
Midazolam is often given before surgery to sedate a patient before anesthesia is given.
Children are often given a small dose either by mouth or squirted into the nose. Children
will often spit out the oral midazolam, making it difficult to know how much medicine, if
any, they have received. Giving midazolam into the nose is more reliable, but children may
complain of pain, stinging, and may become upset due to the discomfort. Nosebleeds may also
occur when midazolam is squirted alone into the nose. The purpose of this study is to see if
adding a numbing medicine, xylocaine, to the nasal midazolam makes giving the midazolam
easier and more comfortable without affecting how the midazolam works as a sedative. This is
follow up to the pilot study, Project # 994. This will expand the previous study, with
additional participants and revised xylocaine concentration