Intranasal Lidocaine for Prevention of Postoperative Nausea and Vomiting.
Status:
Not yet recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
Postoperative nausea and vomiting (PONV) are common and continue to be persistent problems
following general anesthesia. Intranasal lidocaine has been used for the treatment of
migraine. The theoretical basis for this effect of intranasal lidocaine on migraine relief is
reported to be due to its action on the sodium receptors within the sphenopalatine ganglion.
Although there is no reported association between PONV and migraines, injecting lidocaine
within the sphenopalatine ganglion has proven to be effective in reducing PONV in endoscopic
sinus surgery. The purpose of this study is to investigate the efficacy of intranasal 2%
lidocaine in preventing PONV.