Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if intranasal fentanyl can decrease the pain of patients with sickle cell disease who present to the pediatric emergency department with a vaso-occlusive crisis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Montefiore Medical Center
• Treatments: Citric Acid; Fentanyl

Criteria

Inclusion Criteria:

• Sickle Cell Disease

• Ages 3 years - 21 years

Exclusion Criteria for Enrollment:

• Pregnancy

• Known allergy to Fentanyl

• Usage of daily home opiates

Exclusion Criteria at presentation in ED with a painful crisis:

• Wong Baker FACES Pain Score <6

• Systolic blood pressure < 5 percentile for age

• Oxygen saturation <92% on room air

• Temperature > 102°F

• Respiratory distress

• Priapism

• Isolated abdominal pain

• Isolated headache

• New neurological symptoms

• Severe rhinorrhea or epistaxis

• History of trauma

• Pregnancy