Intranasal Dexmedetomidine Sedation for Ophthalmic Examinations in Children

• Status: Unknown status
• Trial end date: 2017-06-01
• Target enrollment: 0
• Participant gender: All

Summary

2 ug/kg of intranasal dexmedetomidine could produce satisfactory sedation in more children for ophthalmic examinations than the sedative effect of 1ug/kg.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sun Yat-sen University
• Collaborator: Ministry of Health, China
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Need sedation for ophthalmic examinations

• Children who had failed chloral hydrate sedation, i.e.there was no evidence of sedation 30 min following administration.

• With informed consent from parents

Exclusion Criteria:

• Children with gastroesophageal reflux

• Children with nausea and vomiting

• Children with apnea in the past three months

• Children with recent pneumonia, exacerbation of asthma, bronchitis and upper respiratory tract infection

• Children with severe arrhythmias, heart failure and cardiac structural abnormalities

• Children with facial abnormalities, who is expected to be difficult with effective mask ventilation

• Children with severe neurological disease

• Children with moyamoya disease

• Children who is allergy to For dexmedetomidine or chloral hydrate

• Preterm children, weight <2 kg