Most patients with preoperative varying degrees of stress, anxiety, which makes the stress
response in patients and affect the normal conduct of anesthesia and surgery.The sympathetic
system hyperexcitability prone to cause adverse cardiovascular events and affect
postoperative recovery. However, phenobarbital, as the traditional premedication, has less
sedative, weak anxiolytic and other shortcomings. Midazolam accompanied by inhibition of
respiration,excessive sedation, easily induced delirium,prolonged recovery time and so on.
Dexmedetomidine is a highly selective α2-adrenergic receptor agonist, it has sedative,
anxiolytic, no inhibition of respiration, and also colorless, odorless, non-mucosal
stimulation, nasal drip ease of administration, patient acceptance, comfortable. Therefore,
dexmedetomidine as premedication has certain advantages. The purpose of this research is to
study sedative effect, safety and the impact of anesthesia recovery period of intranasal
dexmedetomidine premedication for suspension laryngoscopy.
Phase:
N/A
Details
Lead Sponsor:
Guangzhou First Municipal People’s Hospital Guangzhou First People's Hospital