Intrahepatic HCV RNA and Telaprevir Kinetics in Hepatitis C Virus (HCV)
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the decline of virus in the blood and liver in
patients treated with telaprevir, pegylated interferon and ribavirin.
Fine Needle Aspiration (FNA) procedure will be used to repeatedly sample the liver to enhance
the understanding of how the virus decays in the liver in response to treatment with
anti-viral compounds and the measurement of the concentration of the drugs in the liver. FNA
is an alternative procedure to core needle biopsy in its ability to repeatedly sample the
liver with significantly reduced morbidity.