Intragastric Injections of Botox for the Treatment of Obesity
Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
One possible angle for treating obesity could be slowing down the gastric emptying time. By
prolonging the gastric emptying time, the person would ideally experience increased sensation
of satiety, and in the long run reduce food intake. If such a treatment provides a clinically
significant weight loss, this could be an alternative for surgical procedures, avoiding the
risk for perioperative complications as well as complications in the long run.
There are now several pilot studies documenting that intragastric treatment with botulinum
toxin A (BTA) can be effective, although the treatment perspective is short and do not
include repeated injections. However, they demonstrate that BTA-injections are safe for the
patient. The treatment is administered by endoscopy.
Phase:
Phase 2
Details
Lead Sponsor:
Norwegian University of Science and Technology
Collaborator:
St. Olavs Hospital
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA Pharmaceutical Solutions