Intraarticular Injections of the Hip and Knee With Triamcinolone Versus Ketorolac: A Randomized Controlled Trial
Status:
Completed
Trial end date:
2019-08-20
Target enrollment:
Participant gender:
Summary
Clinicians commonly utilize intraarticular injections to treat symptomatic primary arthritis.
Steroid injections are common yet have immune-modulating effects and can alter gene
expression which may delay definitive arthroplasty and further damage cartilage.
Non-steroidal anti-inflammatory (NSAID) injections may offer a safer profile due to their
differing mechanism of action; however, there is a relative dearth of information regarding
their efficacy. This non-inferiority study compares the effectiveness of triamcinolone versus
ketorolac in treating symptoms of moderate to advanced primary osteoarthritis of the hip and
knee.