Overview

Intraarterial Alteplase Versus Placebo After Mechanical Thrombectomy

Status:
Recruiting
Trial end date:
2021-05-31
Target enrollment:
Participant gender:
Summary
Multicenter, randomized, placebo-controlled, double blind, phase 2b trial of acute stroke patients treated with mechanical thrombectomy (MT), in which two therapies are compared: rt-PA or placebo. Allocation at each center will account for 1 stratum: use of alteplase (yes vs. no) before MT. Subjects will be followed up to 90 days post-randomization.
Phase:
Phase 2
Details
Lead Sponsor:
Hospital Clinic of Barcelona
Collaborators:
Fundació La Marató de TV3
Fundacion Clinic per a la Recerca Biomédica
Treatments:
Plasminogen
Tissue Plasminogen Activator