Intra-arterial Versus Intravenous Cisplatin, Combined With Radiation, for Oral Cavity and Oropharynx Cancer
Status:
Terminated
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
This is a randomized, open-label investigator initiated pilot/ feasibility study comparing
the effectiveness of intra-arterial administration of cisplatin therapy to intravenous
administration of cisplatin when each is combined with the radiation therapy found in
standard care. Participants will be randomized to either intra-arterial or intravenous
cisplatin chemotherapy. This study is designed to determine whether a large scale study is
practical in the investigators clinical setting. Approximately 10 subjects will be enrolled
over a 2 year period.