Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET)

• Status: Recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who received recanalization operation.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hui-Sheng Chen
• Treatments: Neuroprotective Agents

Criteria

Inclusion Criteria:

1. Age ≥18 years;

2. Acute ischemic stroke patients who is eligible for endovascular treatment;

3. Signed informed consent.

Exclusion Criteria:

1. Modified Rankin Score >2 caused by a history of prior stroke;

2. Coagulation disorders, systematic hemorrhagic tendency, thrombocytopenia (<80000/mm3);

3. Severe hepatic or renal dysfunction, increase in ALT or AST (more than 2 times of upper limit of normal value), increase in serum creatinine (more than 1.5 times of upper limit of normal value) or requiring dialysis;

4. Severe hypertension (systolic blood pressure over 200mmHg or diastolic blood pressure over 110 mmHg);

5. Unsuitable for this clinical studies assessed by researcher.