Overview Intra-arterial Chemotherapy for Retinoblastoma Status: Recruiting Trial end date: 2024-05-31 Target enrollment: Participant gender: Summary Children with retinoblastoma who may benefit from intra-arterial chemotherapy will receive up to 3 doses of melphalan and will be assessed for feasibility, toxicity, and response. Phase: Phase 1 Details Lead Sponsor: Washington University School of MedicineTreatments: Melphalan