Intra-arterial Chemotherapy for Children With Retinoblastoma
Status:
Unknown status
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
Retinoblastoma is a cancer of the eye that occurs exclusively in children. The treatment for
retinoblastoma may include surgery, chemotherapy, radiation and local treatments to the eye
such as freezing (cryotherapy) and local radiation (brachytherapy). In some cases, a child
with retinoblastoma will have active cancer in a single remaining eye with useful vision. In
such cases, it is sometimes necessary to remove this eye. In such cases, the injection of
chemotherapy directly into the artery that supplies the eye and the tumor may lead to
regression of the tumor without the need to remove the eye.
This form of treatment was pioneered by a group in New York (Abramson et al). In this study
the investigators will assess the efficacy and safety of the technique in a group of children
with retinoblastoma.