Intra-Tympanic Steroid With PRP Combination in Sensorineural Hearing Loss and Tinnitus.
Status:
COMPLETED
Trial end date:
2023-10-21
Target enrollment:
Participant gender:
Summary
Steroids are used widely for the treatment of Sensorineural hearing loss worldwide. The difficulty lies with efficient delivery of the drug into the cochlea, which is already a sealed chamber with limited blood supply that too with an end Artery. We intend to extrapolate its effects by combining it with Platelet rich plasma. intra-tympanic delivery is achieved with injection via tympanic membrane and its absorption via round window is hastened by posture maintenance for about half an hour. PRP is an autologous biologic fluid which has excellent safety profile and is already in use by various specialties.
Phase:
EARLY_PHASE1
Details
Lead Sponsor:
CMH RWP Combined Military Hospital RWP: Rawalpindi