Intra Articular Injection of Ozone With Corticosteroids vs PRGF in Knee Osteoarthritis

• Status: Not yet recruiting
• Trial end date: 2023-10-20
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the effectiveness of intra-articular injection of ozone with corticosteroids versus plasma rich in growth factors (PRGF) in improvement of pain in knee osteoarthritis patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University

Criteria

Inclusion Criteria:

• Patients aged 21-65 years

• both genders

• who will be diagnosed with stage 2-3 knee osteoarthritis according to the Kellgren-Lawrence Classification System (K-L) [10], with WOMAC Score > 2 for pain stiffness and physical disabilities

• having symptoms of Knee OA at least 3 months after getting usual conservative treatment like oral analgesics and Therapeutic Exercises.

Exclusion Criteria:

• Patient refusal.

• Patients who will be diagnosed with Stage 1or 4 OA according to K-L Classification

• History of knee trauma within the past month

• History of malignancies

• Any surgical intervention of the knee

• Local or systemic infection

• Any patient with sever renal Impairment

• Bleeding disorders