Interstitial Cystitis: Examination of the Central Autonomic Network
Status:
Recruiting
Trial end date:
2022-07-01
Target enrollment:
Participant gender:
Summary
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) afflicts 3 to 8 million women in the US.
Symptoms of IC/BPS reduce quality of life, suppressing both social well-being and physical
function. The chronic pain, voiding dysfunction, sleep deprivation and associated co-morbid
conditions interfere with relationships and employment with significant direct (doctor
visits, medication, surgery) and indirect (loss of productivity) economic impact, currently
exceeding $100 million per year.This proposal aims to move the science of chronic pelvic pain
(CPP) from simple associations towards an investigation of cause and effect relationships.
The investigators will determine whether the striking changes in autonomic nervous system
responsiveness (ANS-R) contribute meaningfully to the pathogenesis of IC/BPS.
Phase:
Phase 4
Details
Lead Sponsor:
Medical College of Wisconsin
Collaborators:
Case Western Reserve University NorthShore University HealthSystem