Intermittent Preventive Treatment in Infant in Mali

• Status: Completed
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Studies have shown that Intermittent preventive treatment in infants (IPTi) with Sulfadoxine-pyrimethamine (SP)reduced the incidence of clinical malaria and anemia without modifying infants' serological response to EPI vaccines. Thus IPTi was seen as a potential public health tool of great benefit to the children of Africa and a logical addition to the Immunization Plus package. The objectives of this operational researcher were

• to develop an implementation model for IPTi in the health care system in Mali

• to assess its impact on the EPI vaccines and other health interventions coverage

• and on molecular makers of resistance to SP

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Bamako
• Collaborator: UNICEF
• Treatments: Fanasil, pyrimethamine drug combination; Pyrimethamine; Sulfadoxine

Criteria

Inclusion Criteria:

• Resident of Kolokani, Mali

• Age less than 24 months

Exclusion Criteria:

• Not Resident of Kolokani

• Age of 24 months or above