Interferon-Beta Gene Transfer (Ad.hIFN-β) as Treatment for Refractory Colorectal Carcinoma With Liver Metastases
Status:
Completed
Trial end date:
2006-09-01
Target enrollment:
Participant gender:
Summary
This study will be conducted in subjects with refractory colorectal carcinoma with
unresectable liver metastases. The purposes of the study are:
- to evaluate the safety and any harmful effects of an intravenous injection of Ad.hIFN-β;
- help determine whether the virus carrying the interferon-beta gene will enter the
bloodstream and liver tumor cells and cause the cancer cells to die.