Overview

Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome

Status:
Not yet recruiting
Trial end date:
2023-12-01
Target enrollment:
Participant gender:
Summary
The main objective will be to check if MyoInositol (MYO) reduces the total resistance rate to Clomiphene Citrate (CC). For this, our study will be controlled, randomized and double blinded. It will include patients with PCOS (polycystic ovary syndrome, defined by the Rotterdam criteria) who wish to become pregnant and are eligible to simple ovulation induction by CC. Half of them will receive MYO + folic acid (FA) in addition to the CC, while the other half will receive a placebo containing only FA in addition to the CC. The MYO supplementation will be initiated at least one month before taking CC and will be continued throughout this treatment until pregnancy or before switching to another type of treatment for ovulation induction if no pregnancy is obtained after 6 ovulatory cycles.
Phase:
Phase 3
Details
Lead Sponsor:
University Hospital, Lille
Collaborators:
Laboratoires Besins International
Ministry of Health, France
Treatments:
Citric Acid
Clomiphene
Enclomiphene
Folic Acid
Inositol
Vitamin B Complex
Zuclomiphene