Overview

Interest of Gentamicin-induced Readthrough in Cystic Fibrosis Patients

Status:
Terminated
Trial end date:
2005-06-01
Target enrollment:
Participant gender:
Summary
Suppression of stop mutations in the CFTR gene with parenteral gentamicin can be predicted in vitro and is associated with clinical benefit and significant modification of the CFTR-mediated chloride transport in nasal and sweat gland epithelium.
Phase:
Phase 2
Details
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Treatments:
Gentamicins