Overview

Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors

Status:
Terminated
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
This is a "tissue banking and data review" research study that also has a "clinical" research part: - The goal of the tissue banking part of this study is to store tissue in a research tissue bank by the International Society for Pediatric Oncology (SIOP) at an international reference center for choroid plexus tumors. The tissue will be used in future research related to cancer. - The goal of the data review part of this study is to collect information from the medical records of patients with choroid plexus tumors, and to store the information in SIOP databases for use in future research related to cancer. - The goal of this clinical research study is to compare 4 chemotherapy treatments for choroid plexus tumors. The safety and level of effectiveness of these study treatments will be compared and studied. The study drugs include different combinations of etoposide, carboplatin, vincristine, cyclophosphamide, methotrexate, doxorubicin, cisplatin, dactinomycin, temozolomide, and irinotecan.
Phase:
Phase 3
Details
Lead Sponsor:
Tufts Medical Center
Treatments:
Camptothecin
Carboplatin
Cisplatin
Cyclophosphamide
Dacarbazine
Dactinomycin
Doxorubicin
Etoposide
Etoposide phosphate
Irinotecan
Leucovorin
Liposomal doxorubicin
Methotrexate
Temozolomide
Vincristine