There are mixed reports on nicotine's effects on ethanol-induced impairment in cognitive
performance and behavior in humans. The main objective of this study is to characterize the
interactive effects of acute intravenous (IV) ethanol and nicotine administration on
cognition and behavior in healthy smokers. The general hypothesis is that nicotine will
attenuate the negative effects of ethanol on cognition and subjective stimulant/sedative
effects of ethanol.
Phase:
Early Phase 1
Details
Lead Sponsor:
Yale University
Collaborator:
South Central VA Mental Illness Research, Education & Clinical Center