Overview

Interaction of Apelin and Angiotensin in the Systemic Circulation

Status:
Completed
Trial end date:
2010-04-01
Target enrollment:
Participant gender:
Summary
The apelin-APJ system is a relatively new discovery. It has generated interest in part due to it's apparent ability to counteract the renin-angiotensin system, which is frequently overactive in many cardiovascular disease. Apelin improves that pumping ability of the heart and we wish to know if this action persists in the presence of increased levels of angiotensin II.
Phase:
N/A
Details
Lead Sponsor:
University of Edinburgh
Treatments:
Angiotensin II
Angiotensinogen
Giapreza