Interaction in Chronic Obstructive Pulmonary Disease Experiment
Status:
Completed
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
The final purpose of this study is to determine whether bronchodilation and cigarette smoking
in Chronic Obstructive Pulmonary Disease (COPD) patients interact, resulting in an increase
of cardiovascular disease. The aim of this part of the study is to demonstrate the basic
mechanism: Does increased respiratory function after administration of a bronchodilator in
patients with COPD lead to elevated pulmonary retention of the harmful compounds in inhaled
cigarette smoke and to short-term biological effects associated with cardiovascular disease?