In the postoperative period; pain, nausea, and vomiting are undesirable side effects that
reduce the patient's comfort and may lead to various complications. Ondansetron is frequently
used as an antiemetic and tramadol hydrochloride is used for postoperative analgesia in
laparoscopic cholecystectomy. However, some studies have reported that there is a drug
interaction between these two drugs and they reduce each other's effects, thus requiring more
analgesics in the postoperative period.
The aim of this study is; To evaluate whether ondansetron reduces the analgesic efficacy of
tramadol hydrochloride in laparoscopic cholecystectomies.