Overview

Interaction Between NGF and Acute Exercise-induced Ischemia

Status:
Completed
Trial end date:
2018-06-15
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to investigate pain evoked responses and facilitation of NGF-induced mechanical muscle hyperalgesia over time following an acute exercised-induced ischemic condition in a NGF-sensitized muscle.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Aalborg University
Treatments:
Mitogens
Criteria
Inclusion Criteria:

- Healthy and pain free volunteers

Exclusion Criteria:

- Pregnancy

- Drug addiction defined as the use of cannabis, opioids or other drugs

- Previous neurologic, mental illnesses, or psychiatric diseases.

- Past history of chronic pain in the musculoskeletal system (muscle, joint, cartilage,
connective tissue)

- Participation in other pain trials throughout the study period

- Lack of ability to cooperate

- Taking any analgesic 24 hours before the injections

- Performing any strenuous leg exercise through out the study period causing sore
muscles