Interaction Between Chlorhexidine and Fluoride

• Status: Completed
• Trial end date: 2012-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the present study was to study if there are interactions and reduced clinical effect between chlorhexidine and fluoride when they are combined in the same mouthrinse.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Oslo
• Collaborator: Göteborg University
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Fluorides

Criteria

Inclusion Criteria:

• Male and female subjects, age 18-35 years

• Good general health

• No signs of periodontitis and caries

• A minimum of 24 teeth with no extensive restorations

• No current or planned dental treatment during the trial periods.

Exclusion Criteria:

• Antibiotic treatment within 1 month prior to the start of the trial

• Current medication with anti-inflammatory drugs

• Use of antiseptic mouthrinses

• Smokers and snuff user

• Use of chewing gums