Intensive Versus Conventional Glycemic Control in Diabetic Foot Ulcer Healing
Status:
Unknown status
Trial end date:
2019-06-30
Target enrollment:
Participant gender:
Summary
Diabetic foot ulcer is one of the most serious, most costly and at times life threatening
complication of diabetes. The lifetime incidence of foot ulcer occurrence in diabetes is up
to 25%. Despite the advent of numerous types of wound dressings and off-loading mechanisms,
the ulcer healing rates in diabetes have remained dismally low. Hyperglycemia impairs the
inflammatory, proliferative and remodeling phases of an ulcer. There are retrospective
studies linking improvement of HbA1c to wound area healing rate. The investigators
hypothesised that intensive glycemic control in a patient of diabetic foot ulcer improves the
healing process. To explore this hypothesis, the investigators are conducting this randomized
control trial with the primary aim of wound healing in patients of diabetic foot ulcer on
either intensive glycemic treatment or conventional (pre-existing) glycemic treatment.
Phase:
N/A
Details
Lead Sponsor:
Postgraduate Institute of Medical Education and Research