Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

• Status: Completed
• Trial end date: 2007-12-01

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known if stronger doses of chemotherapy given over a longer period of time are as well tolerated or as effective as less intensive chemotherapy.

PURPOSE: This randomized phase III trial is studying intensive regimens of chemotherapy to see how well they work compared to nonintensive regimens of chemotherapy in treating older patients with acute myeloid leukemia or myelodysplastic syndrome.

• Phase: Phase 3

Details

• Lead Sponsor: Leukemia Research Fund
• Treatments: Cytarabine; Daunorubicin; Etoposide; Hydroxyurea; Idarubicin; Mitoxantrone; Thioguanine; Tretinoin