Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to
the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in
chemotherapy, such as fluorouracil and mitomycin C, work in different ways to stop the growth
of tumor cells, either by killing the cells or by stopping them from dividing. Giving
radiation therapy together with 5-fluorouracil (5-FU) and mitomycin C may kill more tumor
cells.
PURPOSE: This phase II trial is studying the side effects and how well giving
intensity-modulated radiation therapy together with fluorouracil and mitomycin C works in
treating patients with invasive anal cancer.