Intact Liver Innervation and Glucose and Glucagon-like Peptide-1 (GLP-1) Induced Insulin Secretion
Status:
Unknown status
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The aim of the study is to investigate the significance of intact nerve supply to the liver
for the glucagon-like peptide-1 (GLP-1) induced insulin secretion.
The hypothesis is that the effects of GLP-1 is transmitted through the GLP-1 receptor and
that these effects involve sensory afferent neurons, probably primarily parasympathetic.
Phase:
N/A
Details
Lead Sponsor:
University Hospital, Gentofte, Copenhagen
Collaborator:
University of Copenhagen
Treatments:
Dipeptidyl-Peptidase IV Inhibitors Glucagon Glucagon-Like Peptide 1 Insulin