Insulin Therapy in the Hospital Comparing Two Protocols

• Status: Completed
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if by using insulin analog (Glargine and lispro insulin) with an insulin pen the investigators are able to obtain a higher rate of correct timing of insulin and food administration as when compared to the usual therapy (insulin NPH and regular) with syringes.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: John H. Stroger Hospital
• Collaborator: Eli Lilly and Company
• Treatments: Insulin; Insulin Glargine; Insulin Lispro; Insulin, Globin Zinc; Insulin, Isophane; Isophane insulin, beef; Isophane Insulin, Human

Criteria

Inclusion Criteria:

• Uncontrolled blood sugar:

• Random blood sugar ≥ 200mg/dl

• Pre-prandial blood sugar greater than 180 mg/dl on two occasions within 24 hours.

• Patient may be off insulin or on subcutaneous inpatient insulin regimen less than 36 hours.

• Transition from an Insulin Drip in the intensive care units to subcutaneous insulin upon transfer to general ward.

• Patient is able to eat and oral feeding is expected.

Exclusion Criteria:

• Patients receiving inpatient oral hypoglycemic agents

• Patients with chronic kidney disease stages 4 & 5 (estimated GFR of <30ml/min) and on dialysis

• Patient with chronic liver disease

• Patient with hypoglycemia unawareness

• Pregnancy

• Patients who are on "NPO" for medical reasons.

• Patient is expected to stay in the hospital for less than 3 days.

• Patient on a new inpatient insulin regimen for > 36 hours.