Overview Insulin Signaling in Skeletal Muscle Status: Withdrawn Trial end date: 2025-06-01 Target enrollment: Participant gender: Summary The insulin sensitizing effects of metformin and pioglitazone in the skeletal muscle remain unknown. Our group aims to analyze molecular changes within the skeletal muscle of pre-diabetic patients through the use of a clinical trial in humans. Phase: Phase 2/Phase 3 Details Lead Sponsor: Wayne State UniversityTreatments: MetforminPioglitazone