Insulin Sensitivity in Men With the Metabolic Syndrome
Status:
Suspended
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
The metabolic syndrome is a medical condition defined by high levels of cholesterol in the
blood, high blood pressure, central obesity (gain in fat around the region of the stomach),
and insulin resistance (body responds less well to insulin). This state of impaired insulin
resistance can lead to type 2 diabetes mellitus, which is one of the most common metabolic
disorders in the U.S. Numerous studies have shown an inverse relationship between insulin
resistance and testosterone levels in men, however, causality has not been established. This
protocol investigates the role of testosterone in modulating insulin sensitivity in insulin
resistant states such as the metabolic syndrome. The hypothesis is that testosterone
administration will improve insulin sensitivity.
Phase:
N/A
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)