Insulin Requirement for Pure-protein Meal in Children With Type 1 Diabetes on Insulin Pumps.

• Status: Unknown status
• Trial end date: 2018-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a randomized, cross-over study. The aim of this study is to compare the post-prandial glycaemic variability after pure protein meal following with an administration of square-wave bolus of meal-insulin or without any meal-insulin bolus on the other day.

Prolonged post-prandial glycaemic variability will be identified using the self-monitoring of blood glucose (10-point curve) and CGMS.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Warsaw
• Treatments: Insulin; Insulin Aspart; Insulin degludec, insulin aspart drug combination; Insulin glulisine; Insulin Lispro; Insulin, Globin Zinc; Insulin, Long-Acting

Criteria

Inclusion Criteria:

• duration of type 1 diabetes longer than 12 months

• insulin pump therapy longer than 3 months

• written informed consent by patients and parents

• insulin requirement more than 0,5 units/kg/day

Exclusion Criteria:

• diabetes related complications (e.g. nephropathy)

• chronic kidney diseases

• any disease judged by the investigator to affect the trial

• withdrawal of consent to participate in the study