Injection Free IVF

• Status: Not yet recruiting
• Trial end date: 2024-03-31
• Target enrollment: 0
• Participant gender: Female

Summary

Investigation of Natural Cycle In vitro Fertilisation (NC-IVF) treatment with ovulation induction with a nasal GnRH agonist instead of regular NC-IVF treatment with subcutaneous application of hCG with the objective of increasing treatment tolerability and reducing discomfort while being equally successful in terms of embryo transfer rates.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital Inselspital, Berne
• Treatments: Nafarelin

Criteria

Inclusion Criteria:

• Indication for IVF

• Wish to perform NC-IVF

• Regular menstruation cycles (26-32 days)

• Orthotopic localization of ovaries

• Age 18-42

• Written informed consent

Exclusion Criteria:

• Endometrioses III°-IV°

• ≥ 3 embryo transfers in previous IVF therapies without pregnancy

• Contraindications or allergies against study medications

• < 18 and > 42 years of age

• Known or suspected non-compliance

• Inability of the participant to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.

• Participation in another study with investigational drug within the 30 days preceding and during the present study

• Previous enrolment into the current study

• Enrolment of the investigators, their family members, employees and other dependent persons