Injectable Platelet Rich Fibrin With Non Surgical Periodontal Therapy

• Status: Unknown status
• Trial end date: 2020-01-25
• Target enrollment: 0
• Participant gender: All

Summary

Clinical evaluation of local subgingival application of injectable platelet-rich fibrin ( i-PRF ) for chronic periodntitis as adjunctive to non surgical therapy and compare it with hyaluronic acid.

120 periodontal patients will receive a scaling and root planing ( non surgical periodontal therapy). Equal number of patients will receive subgingival application of i-PRF, hyaluronic acid or placebo gel as the adjunction to non surgical therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Institute of Dental Sciences, Bareilly, Uttar Pradesh, India
• Treatments: Hyaluronic Acid

Criteria

Inclusion Criteria:

• Patients are in general good health.

• Patients having minimum of 20 permanent teeth.

• They have not taken medication known to interfere with periodontal tissue health or healing in the preceding 6 months.

• Presence of periodontal pockets (≥5 mm) and clinicala ttachment level > 5 mm.

Exclusion Criteria:

• Immunosuppressive systemic diseases (like cancer, AIDS, diabetes etc.)

• Clotting and Hematological disorders

• Patients with grade III mobility.

• Patients with smoking and alcohol consuming habit.

• Pregnant and lactating female.

• Medications influence on the gingival and periodontal tissues (like calcium channel blockers, or Long-term steroid use)

• The teeth with poor filling and ill fitted restorations