Overview

Inhibition of Anaphylaxis by Ibrutinib

Status:
Completed
Trial end date:
2018-11-14
Target enrollment:
Participant gender:
Summary
This is a phase II open label study on the use of Ibrutinib on the inhibition of food-induced anaphylaxis in adults with food allergy. Ibrutinib (brand name Imbruvica) is currently FDA approved for the treatment of mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), and Waldenstrom's macroglobulineia (WM). We propose to administer this approved drug to adults with food allergy to inhibit food allergy responses.
Phase:
Phase 2
Details
Lead Sponsor:
Ann & Robert H Lurie Children's Hospital of Chicago
Collaborator:
Feinberg School of Medicine, Northwestern University