Inhaled NO in Surgical Patients With Recent COVID-19 Infection
Status:
Not yet recruiting
Trial end date:
2024-01-31
Target enrollment:
Participant gender:
Summary
The aim of this study is to evaluate the effect of perioperative inhalation of NO on reducing
the incidence of postoperative pulmonary complications in patients with recent COVID-19
infection, and to evaluate whether inhaled NO can improve the prognosis of patients.
The investigators will enroll 660 surgical patients who was infected with SARS-CoV-2 within
42days (7 weeks ) prior to planed surgery under general anesthesia. Patients will be
randomized to receive either inhaled nitric oxide (per protocol) or a placebo. Perioperative
standards of care will be the institution's own protocols (such as ventilation strategies and
use and dose of anesthetics, analgesia and fluid management, etc).