Inhaled NO in IPF and COPD During 6 Minute Walk Test

• Status: Recruiting
• Trial end date: 2020-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Our objective is to evaluate the influence of inhaled NO on the saturation and exercise capacity of patients with COPD and IPF. each participant will undergo two six minute walk tests, one with inhaled NO and the other with placebo.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rabin Medical Center
• Collaborator: Bellerophon
• Treatments: Nitric Oxide

Criteria

Inclusion Criteria:

1. Patients with COPD with disease severity of GOLD stage 3-4

2. Patients with IPF with a Forced vital capacity under 80% and a diffusion capacity under 60%

3. Ambulatory patients that can perform a 6-minute walk test

Exclusion Criteria:

1. Patients with moderate to severe heart failure - EF < 40%

2. Patients with severe PVD or scleroderma