Inhaled Corticosteroids on Airway Smooth Muscle in Asthma
Status:
Withdrawn
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
The main objective is to evaluate how treatment with inhaled corticosteroids (ICS) affects
the characteristics of airway smooth muscle (ASM) cells from asthmatic subjects. Our
hypothesis is that airway smooth muscle cell dysfunction plays an important role in the
pathogenesis of asthma, and that treatment with inhaled corticosteroids reverses the
abnormalities in airway smooth muscle cell function.