Overview

Influencing Factors of Helicobacter Pylori Infection and Eradication Failure

Status:
Recruiting
Trial end date:
2023-03-01
Target enrollment:
0
Participant gender:
All
Summary
Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric cancer and other diseases, the discovery and eradication of H. pylori infection has great significance to the prevention and treatment of related diseases. At the same time,understanding the influencing factors of H. pylori infection and eradication failure in the population can provide a scientific basis for the formulation of local H. pylori prevention and control strategies. So, the investigators intend to analyze the factors related to H. pylori infection and eradication failure in the outpatients of gastroenterology clinics in Xi'an, China.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Second Affiliated Hospital of Xi'an Jiaotong University
Criteria
Inclusion Criteria:

1. Perform 13-UBT,

2. Be able to understand the content of the questionnaire and answer the questions
accurately,

3. Permanent residents of Xi'an area,

4. No previous HP eradication treatment,

5. Agree to join the group and sign the informed consent form,

6. Aged between 18-70.

Exclusion Criteria:

1. Complicated with serious cardiovascular, respiratory, blood, liver, kidney, nerve or
endocrine system diseases,

2. Mental disease,

3. Gastric or esophageal surgery history,

4. Severe atypical hyperplasia of gastric epithelium, gastric malignant tumor or other
malignant diseases

5. Pregnant or lactating women,

6. Patients with history of penicillin allergy,

7. Allergy to rabeprazole, bismuth dose, clindamycin,

8. Have taken proton pump inhibitors,H2 receptor antagonists, within 2 weeks before
participating in the inspection,

9. Have taken herbs that have bacteriostatic effect or antibiotic or bismuth agents
within 4 weeks before participating in the inspection.