Influence of a Bolus Administration of Ephedrine and Phenylephrine on the Spinal Oxygen Saturation, Measured With NIRS.
Status:
Completed
Trial end date:
2018-12-04
Target enrollment:
Participant gender:
Summary
To evaluate the influence of vasoactive medication on the spinal vasculature, we have chosen
patients scheduled for arterial dilation of the lower limb as our study population. In these
patients the spinal cord perfusion is not compromised. However, most patients will suffer
from hypotension during surgery, due to the non-invasive type of surgery and the vasodilating
effects of the anesthetics. Therefore, bolus administration of vasoactive medication
(ephedrine, phenylephrine) is routinely required in order to increase the blood pressure.
The aim of the study is to observe the influence of a bolus administration of ephedrine and
phenylephrine on the spinal vasculature, measured by NIRS.