Influence of Vitamin D Supplementation on Serum BDNF Level and Cognitive Function in Schizophrenia
Status:
Not yet recruiting
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The objective of the study is to evaluate the influence of vitamin D supplementation on Serum
Brain Derived Neurotrophic Factor level and cognitive function in schizophrenia treated with
atypical antipsychotic. Methods: The investigator will use randomized controlled trial
design. 40 chronic schizophrenia patients with vitamin D insufficiency or deficiency treated
with atypical antipsychotic, will be randomly assign (1:1 ratio) to receive either daily oral
cholecalciferol 2000 IU or placebo for 8 weeks. Assessment of BDNF serum and cognitive
function will be performed at baseline and after 8 weeks period.
Phase:
Phase 3
Details
Lead Sponsor:
Universitas Padjadjaran
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins