Influence of Triflusal on Cognitive Functions in Healthy Subjects

• Status: Completed
• Trial end date: 2015-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the effects of the eNOS activating agent triflusal on episodic memory and cognitive functions in healthy participants.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Prof. Dominique de Quervain, MD
• Treatments: Mannitol; Salicylates; Triflusal

Criteria

Inclusion Criteria:

• Healthy

• Male or female

• Normotensive

• BMI between 20 and 27 kg/m2

• Aged between 18 and 40 years

• Native or fluent German-speaking

• Caucasian

• Female practicing safe contraception

Exclusion Criteria:

• Acute or chronic psychiatric or somatic disorder

• Any contraindication against aspirin or other NSAIDS

• History of coagulation disease

• History of gastrointestinal disease

• Laboratory exclusion criteria: values of blood count, blood chemistry and coagulation status outside normal range

• Pathological ECG

• Pregnancy, breast-feeding