Overview

Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis

Status:
Completed
Trial end date:
2017-05-12
Target enrollment:
Participant gender:
Summary
Purpose 1. To compare the performance of the two currently employed urinary acidifications tests in stone formers, the furosemide/fludrocortisone and ammonium chloride loading test. 2. To study the impact of polymorphisms in the genes ATP6V1B1, ATP6V0A4 and SLC4A1 on urinary acidification in stone formers.
Details
Lead Sponsor:
University Hospital Inselspital, Berne
Treatments:
Fludrocortisone
Furosemide