Influence of Oxycodone on Individuals Taking an SSRI
Status:
Not yet recruiting
Trial end date:
2025-04-15
Target enrollment:
Participant gender:
Summary
This study will determine whether selective serotonin reuptake inhibitors (SSRI) exacerbate
opioid induced respiratory depression in patients initiating treatment for underlying
conditions such as depression or an anxiety disorder. Next to paroxetine which has been
evaluated in a previous study in healthy volunteers sertraline, citalopram and escitalopram
will be evaluated with regards to its influence on opioid induced respiratory depression.