Influence of G-CSF and EPO on Associative Learning and Motor Skills

• Status: Completed
• Trial end date: 2009-03-01
• Target enrollment: 0
• Participant gender: All

Summary

In the study we want to prove whether the subcutaneous application of granulocyte-stimulating factor (G-CSF) and erythropoetin (EPO) influence associative learning and/or motor skills of patients, who suffer from chronic stroke or amyotrophic lateral sclerosis. The study hypothesis is that G-CSF and EPO improve associative learning and/or motor skills.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Muenster
• Treatments: Epoetin Alfa; Sargramostim

Criteria

Inclusion Criteria:

• Diagnosis of chronic stroke or amyotrophic lateral sclerosis

Exclusion Criteria:

• leucocytes > 10000/µl

• hematocrit > 48%

• thrombocytes < 150000/µl

• severe rheumatoid arthritis

• severe infection

• severe liver or renal failure

• severe arterial hypertension

• recurrent thromboembolic events

• severe coronary heart disease

• myocardial infarction

• malignant tumor

• leukemia

• peripheral arterial occlusion disease