Influence of Esophageal Washout on Local Carcinoma Recurrence After Curative Resection

• Status: Recruiting
• Trial end date: 2022-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The LOCARE-Trial is an investigator initiated, randomized-controlled trial with two parallel arms (n=60 each) and investigates the influence of esophageal washout on long-term outcomes in patients undergoing elective esophageal resection for carcinoma. The primary endpoint is defined as local carcinoma recurrence. Secondary endpoints will be locoregional and distant recurrence, disease-specific survival and esophageal cancer specific survival.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Technische Universität Dresden
• Treatments: Iodine; Povidone; Povidone-Iodine

Criteria

Inclusion Criteria:

• Patients scheduled for elective esophageal resection or esophagectomy

• Age equal or greater than 18 years

• Written informed consent

• Squamous cell carcinoma of the esophagus (SCC)

• Adenocarcinoma of the gastroesophageal junction (AEG) Type I

Exclusion Criteria:

• Local irresectability or metastatic disease

• Adenocarcinoma of the gastroesophageal junction Type II and III

• Histopathological R1-resection

• Surgery for recurrence

• Iodine allergy

• Hyperthyreosis