Influence of Endothelial Function on Central and Peripheral Causes Of Exercise Impairment in Type 2 Diabetes
Status:
Completed
Trial end date:
2011-10-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the effects of impaired blood flow regulation on exercise. It will
also determine whether the effects are more important in the heart or in the skeletal muscle
tissue during exercise. In addition, this study will decide whether temporarily reversing
these problems will improve blood flow control, improve heart and muscle tissue function and
help improve exercise capacity in person with type 2 diabetes. This study will do so using
two methods: (1) by giving vitamin C intravenously (IV) and (2) a three month exercise
training program. Up to 100 subjects will be enrolled in this study.
Phase:
N/A
Details
Lead Sponsor:
University of Colorado, Denver
Collaborators:
American Diabetes Association National Institutes of Health (NIH)